Sr. Program Manager

Our small molecule company here in Cambridge, MA is looking to add a Sr. Program Manager, PMO to their team!  This role will play a critical role in supporting their lead development program as well as potentially support additional clinical or lifecycle management programs and other company-wide initiatives. This individual will be part of a team of project managers in the PMO and will work closely with cross-functional Global Program Teams (GPTs) to ensure robust integrated program management. In collaboration with the functional representatives, they will prepare project plans that are in line with the overall program goals, track progress, and mitigate issues.  They will be responsible for driving effective communication across the organization and between internal stakeholders. They may also directly interact with our external partners. The ideal candidate will have project management experience in addition to a scientific background and experience with clinical-stage drug development / commercialized products.


  • Provide project management, coordination, and cross-functional communication to ensure achievement of program goals and timelines.
  • Implement program management tools and templates to facilitate effective planning and communication.
  • Manage the development of the integrated project plan (timeline, milestones, deliverables) in collaboration with cross-functional stakeholders.
  • Ensure timely, accurate and comprehensive project information is available for governance meetings and/or for wider R&D communication.
  • Manage the operation of the GPT (scheduling meetings, sending agendas, defining meeting objectives, preparing minutes, and following-up with team members on critical action items).
  • Manage GPT sub-teams as needed.
  • Play a critical role in helping the team identify project risks, perform regular risk assessments, understand the impact of project risks, and implement mitigation strategies.
  • Maintain program-related documentation (including the MS project plan, decision log, risk register and key risks mitigation plan) and ensure appropriate archiving and access to shared information and critical program documents.
  • Implement/pilot tools/technology within Program Management, or the GPT to enable collaborative work and improve efficiency.
  • Drive day-to-day performance oversight through the execution of the project plan, enabling in-depth discussion, holding team members accountable for functional delivery of plans.
  • Facilitate effective decision making by coordinating project team meetings with clear agendas and meeting materials to track issues/actions/decisions.
  • Communicate information about project status and risks to functional and leadership levels, as well as elevate issues, present recommendations and implement modifications to project plans.



  • Bachelors’ / Masters’ degree.
  • 6+ years of relevant Program or Project Management experience in the Biotech /Pharma industry. Project Management (PMP) certification a plus
  • Experience in late-stage drug development and large, global clinical development programs required.
  • Ability to drive decision-making and accountability in a cross-functional matrix environment through strong influence and leadership skills.
  • Strong problem-solving skills, ability to see the big picture with excellent attention to detail.
  • Highly motivated and an effective team player who can thrive in a fast-paced environment, balancing multiple priorities.
  • Advanced communication and relationship building skills, including the ability to interface across functions internally as well as with external partners.
  • Strong analytical and technology skills, including proficiency in project planning tools, content management tools, and Microsoft Project.
  • Strong presentation and writing skills.