Our Immunotherapy start-up client located in Cambridge, MA is growing and looking to add Associate Sci/Sr. Associate Scientists to their Target Discovery team! This growing team is focused on identifying potent tumor killing targets. We are seeking a talented and collaborative molecular/cell biologist to perform and develop large scale screening studies, technology optimization and confirmatory assays. A successful candidate will work closely with team members to drive discovery and pre- development programs. Our dynamic and innovative culture favors highly organized candidates, eager to learn and confident to work across boundaries.
• Work internally with collaborators to advance novel, published and unpublished targets to develop clinical candidates.
• Work with Principal Scientists in the design, execution, and analysis of in vitro cell-based assays utilizing cancer cell lines and primary cells
• Support assay development and execution of company platform, including but not limited to large scale functional genomic screens for hit identification and triaging.
• Contribute effectively to meetings, reports, patents, scientific publications, and company culture.
• Bachelor’s or master’s degree in biology, biochemistry or a relevant scientific discipline and 1-5 years experience in industry or academia
• Cell culture experience using and preparing primary cells, cell lines, and working with lentivirus
• Experience working with CRISPR is a plus but not required
• Prior experience with functional genomics approaches is highly beneficial
• Experience with cell biology skills such as western blotting, immunoprecipitation and immunofluorescence is preferred
• Molecular biology experience with mammalian DNA/RNA extraction, PCR/ RT-PCR/ qPCR
• Able to work efficiently both independently and in a team environment, demonstration of quality, proficiency, and attention to details.
• Maintain clear and accurate records of experiments and analysis in electronic notebook
• Excellent written and communication skills, ability to organize and present scientific data.