Sr. Associate Scientist, Flow Cytometry

Our growing Gene Therapy Client here in Cambridge is growing and looking to add a Sr. Associate Scientist, Flow Cytometry to their Analytical Development team!  Their mission is to pioneer controllable cell and gene therapies to deliver transformative outcomes for patients.  The Analytical Development group is responsible for providing analytical protocols and data on reagents and controls for the development of engineered cell therapies.  This role will be responsible for developing and running assays and advancing product development by delivering critical capabilities in core technologies and key reagents. Sr. Associate Scientist will work collaboratively with others on the team as well as the Vector Process Development, Cell Therapy and Protein Engineering groups to develop platform analytics to support viral vector production, construct screening and engineered cell therapies.  Responsibilities include but not limited to: 


  • The ideal candidate would have expertise in multi flow cytometry within Immunology
  • Design, plan, and execute experiments in Analytical Development working both independently and as part of a multidisciplinary team
  • Develop and/or improve methods in collaboration with research and vector process development to characterize viral vector production methods and primary cell transduction (ex. T cell, TIL, NK cell)
  • Support introduction of new analytical technologies, implementation of common reagents and controls, trending data, and protocols to support construct screening, research studies, research vector production, and CDMO tech transfer activities
  • Maintain excellent records of experiments, including Electronic Notebook entries, authoring of protocols, test methods, and study reports



  • BS/MS or Ph. D. in a relevant discipline (molecular biology, cell biology, biomolecular engineering, biotechnology or relevant field)
  • Minimum of 5-7 years (BS/MS) or 1-3 years (PhD) relevant industrial experience with prior direct experience with multi-flow cytometry required
  • Demonstrated track record with analytical techniques focused on cell biology, immunology and molecular biology
  • Tissue culture of adherent and suspension cell lines, including transfection and viral transduction
  • Subject matter expertise in early stage analytical development, including methods such as cell line/ primary cell transduction/ transfection, multicolor flow cytometry/ FACS, qPCR/ ddPCR, ELISA, MSD, and western blot



  • Experience in analytical development supporting early and/ or late stage development of biologics is highly desirable (cell therapy, gene therapy, vaccines, antibodies)
  • Experience in primary cell gene delivery, including cell types such as T cells, TILs, NK cells
  • Familiarity with viral vector production and cell line engineering
  • Experience with Design of Experiment and application to analytical development