Thank you for checking on this. I changed the description of the job to better reflect what I am looking for. So we are essentially looking for someone with some retinal disease experience but also who has some understanding or experience developing a program preclinical (which I think is hard to find). Someone who ruined Efficacy/Dose Range Finding Studies, GLP Tox studies, wrote preclinical reports that were part of IND submission (or equivalent). If not, someone who understand the preclinical development strategy of a product, which is quite different from early discovery/lead optimization.
Hope it helps!
Scientist II/Senior Scientist, Preclinical Development
South San Francisco, California
Our client’s company is based on the science of one of the original CRISPR co-inventors who then furthered the technology so that DNA does not need to be cut to accomplish gene regulation. They are looking for exceptional team members who want an active role in building a rapidly growing biotech.
Roles and responsibilities:
- Design, conduct, analyze, interpret, and report data on gene therapy program in support of the company’s retinal disease programs.
- Collaborate across our Research and Development divisions to drive projects progression toward key milestones
- Develop strategies for preclinical development, including the identification and management of risks and opportunities.
- Contribute to IND and IP filing
- Ph.D. in cellular and/or molecular biology, ophthalmology, neuroscience, or a related field, with a minimum of 2 years of related experience in biotechnology or pharmaceutical industry.
- Strong preclinical experience in gene therapy
- Experience in designing and overseeing preclinical studies and interpreting preclinical data
Technical Requirements and Skills:
- Ideal candidates will have a deep knowledge of and experience in the genetics of retinal diseases
- Prior experience in developing in vitro and in vivo model systems for retinal diseases
- Strong organizational and documentation skills, effective verbal/written communication skills, and critical problem-solving/analytical skills
- Demonstrated ability to work with CRO and to collaborate with cross-functional teams and external partners, including regulatory agencies, academic institutions, and biotech companies.
- Able to work both independently and collaboratively in a fast-paced, interdisciplinary team
The salary range for this position is $120,000 USD to $170,000 USD annually. This salary range is an estimate, and the actual salary may vary based on various factors, including, without limitation, individual education, experience, tenure, skills, and abilities, as well as internal equity and alignment with market data, including potential adjustments for geographic location.