Overview
We’re working with a pre-series A biotech developing a game-changing drug delivery platform! They are working on oral delivery of biologics for drugs that have only been available via injection.
They are looking for a Senior Scientist to aid in the formulation of novel oral products (peptides, proteins, small molecule, etc). You’ll be an integral part of a small, multi-functional team, helping move products from Discovery through Pre-clinical phases, and support CMC, clinical and IND activities.
Summary
The qualified candidate brings hands-on expertise in state-of-the-art formulation production theories, principles, methods, and techniques for targeted delivery of proteins. You’ll help plan and execute developmental programs for a wide variety of pipeline products. You’ll maintain continual knowledge on the latest trends, methods, improvements, and functions of currently used pharmaceutical drugs.
Responsibilities:
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Formulation of orally delivered biologic drugs
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Execute appropriate investigational procedures that are pertinent to the reactions, composition, relationships, structure, and properties of the compounds and products
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Analyze the material and chemical characteristics of the formulation substances using standard methods (titration, FT-IR, HPLC, ELISA, MSD, DSF, CD, DLS)
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Identify new techniques, tools, and procedures to analyze formulations
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Conduct in vitro and in vivo (small animal) studies to test formulations
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Support the development of products through CMC by preparing quality assurance documentation, including formulation specifications
Qualifications
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PhD in pharmaceutical science, biological/chemical engineering, or a related field
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5+ years of hands-on industry experience in protein (or similar biologics) drug formulation
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Deep knowledge about basic and advanced concepts in materials science and pharmaceutical development