Research Associate II/Senior Research Associate, CRISPR Technology Development
South San Francisco, CA
Who Are We?
Our client’s company is based on the science of one of the original CRISPR co-inventors who then furthered the technology so that DNA does not need to be cut to accomplish gene regulation. They are further evolving the platform and leveraging its strengths to address unmet medical needs.
The successful candidate will develop and execute high-throughput experiments in mammalian cell lines, and work collaboratively with colleagues to build discovery pipelines that enable potentially transformative technologies for a variety of current and future therapeutic indications. They will contribute broadly across multiple technical areas to accelerate the development of programmable epigenetic editing as a therapeutic modality.
- Implement high-throughput screening platforms for gene & protein expression analysis
- Develop DNA constructs, CRISPR libraries, and engineered cell lines
- Coordinate tasks across multiple projects, demonstrating prioritization and planning
- Design, execute, and interpret experiments in line with project timelines and strategic goals
- BS in molecular biology, biochemistry, bioengineering, or related fields, with minimum 3+ years of relevant research experience in industry or academia, or MS in related discipline with minimum one year of experience
- 2+ years’ experience in molecular cloning and mammalian cell culture
Proficient working knowledge and experience in any of the following:
- Flow cytometry, FACS, ELISA, RT-qPCR
- Design & delivery of plasmids and lentiviral vectors into multiple primary and/or immortalized cell types
- High-throughput pooled and/or arrayed CRISPR screening
- Lentiviral vector design, packaging, transduction, and cell line creation
- NGS Illumina library preparation
- Data analysis in R, Python, JMP, Prism, or similar
The salary range for this position is $90,000 USD to $110,000 USD annually. This salary range is an estimate, and the actual salary may vary based on various factors, including, without limitation, individual education, experience, tenure, skills, and abilities, as well as internal equity and alignment with market data, including potential adjustments for geographic location.