Scientist, Ophthalmology

Scientist I/II, Ophthalmology
South San Francisco, CA

The Scientist I/II, ophthalmologic specialist, is responsible for designing and executing experimental plans for eye disease modeling in Therapeutic Team. This individual will establish and support the in vivo and in vitro model systems for eye disease indications. This position includes technically diverse bench work and the training of junior research staff in techniques and equipment used to support drug development and target validation.

Your Role as Scientist I/II:

  • Design and apply cell-based assays to support the target discovery, validation, and characterization of novel epigenetic based therapy
  • Design and perform in vitro and ex-vivo experiments for cellular disease modeling
  • Contribute to the design and optimization of experiments and stay current on literature and technological advances
  • Collaborate with cross-functional teams on array/high throughput screening and drug development projects
  • Contribute to IND and IP filing

Job Requirement:
For Scientist I:

  • Ph.D. with training in ophthalmology, neuroscience, or related fields.
  • 0 – 1 year of industry laboratory experience

For Scientist II:

  • Ph.D. with training in ophthalmology, neuroscience, or related fields.
  • 2-4 years of industry laboratory experience
  • Ideal candidates will have a deep knowledge of and experience in the genetics of eye diseases
  • Prior experience in developing in vitro and in vivo model systems for eye diseases
  • Familiar with various gene therapy delivery systems
  • Strong organizational and documentation skills, effective verbal/written communication skills, and critical problem-solving/analytical skills
  • Able to work both independently and collaboratively in a fast-paced, interdisciplinary team

Nice to have

  • Familiar with CRISPR mediated epigenetic regulation
  • Experience with lab automation for high throughput cell-based screening assay
  • Experience with coding (R, Python)