Scientist I/II, Biochemistry

Our client is a Series C, pre-IPO oncology discovery company in Cambridge with well recognized founders and innovative chemistry beginning clinical trials.  They are seeking a Scientist to join a small group focused on 

The main function of this role is to profile the biochemical and biophysical activity of novel peptide therapeutics and develop a deep understanding of their mode of action. 

Responsibilities include but are not limited to;
•  Lead the design and implementation of robust and rigorous screening strategies to evaluate protein-protein and protein-ligand interactions.
•  Elucidate the mode of action of novel peptide therapeutics towards the intended target through the application of biochemical, biophysical and enzymological methods.
•  Proactively evaluate new technologies, be fully versed with current research literature, and implement new features and functionality into the company’s screening platform.

Formal descriptions can be supplied for interested candidates. 

Qualified candidates will have a PhD in Biochemistry or related discipline and 2 – 5 years of experience post PhD, preferably with at least 2+ in a drug discovery setting.  
Seeking those with experience with biochemical protein-protein interactions and activity-based assay technologies (FP, SPR/Biacore, TR-FRET, Alpha Screen) and experience developing and running plate-based assays.  Hands-on experience with laboratory automation and/or familiarity with interpretation of protein structural models is greatly desired.  

Must be commutable to the Boston/Cambridge area or able to relocate with very limited assistance.  

All resumes will be kept strictly confidential until you choose to pursue a specific opportunity with one of our clients.