Principal Scientist, Oncology

HireMinds has partnered with a pioneer in advanced systems for drug discovery.  They are revolutionizing preclinical drug discovery with their cutting edge technology and microphysiological systems.

We are looking for a Principal Scientist who will be a hands-on technical team lead for our oncology program. You will collaborate with a team of bioengineers, material scientists, and biologists to deliver on milestones set up for our programs, ensuring to meet timelines and present desirable results. The successful candidate will be self-motivated and have demonstrated exceptional communication, organizational, and leadership skills to work in a fast-paced environment.


  • Design, plan, and manage cell-based assays and experiments according to program objectives

  • Define and adapt program goals based on experiment results

  • Evaluate, analyze and report experiment results

  • Manage team of scientists to deliver on program objectives

  • Stay abreast of the latest scientific understanding in project specific biology from target validation to clinical data


  • Advanced degree (MS or PhD) 

  • Significant industry experience in oncology drug discovery

  • Expertise in primary and stem cell culture

  • Experience with design, execution, and analysis of diverse cell biology and tissue engineering experiments

  • Experience with advanced microphysiological models or 3D culture systems

  • Extensive experience documenting, analyzing, interpreting experimental data

  • Experience in drug discovery, hit-to-lead process 

  • Proficiency in a broad range of molecular and cellular techniques including: target engagement assays, western blotting, qPCR, transfection, immunofluorescence, flow cytometry, cell-based functional assays

  • IHC, RT-PCR, histology, ELISA, Western blotting

  • Hands-on experience with fluorescence and confocal microscopy

  • Mechanical analysis and characterization

  • Strong written and verbal communication skills