Principal Scientist, Molecular Biology

Senior Scientist, Molecular Biology 

 

HireMinds is representing a Stealth Mode company coming out of MPM Capital focusing on RNA/ LNP delivery. As they look to revolutionize RNA therapies, they're looking for a Scientist/ Senior Scientist to join their Molecular Biology team!

This is an exciting opportunity for the ideal candidate to contribute to a well-funded early-stage biotech. This role is in Cambridge, MA with plans to move to a new start-of-the-art facility in Boston early 2022. The Scientist will have a huge impact within a high growth startup. The position comes with competitive compensation and a spot on a talented team.

Job Responsibilities

  • Independently design, plan, and execute in vitro experiments to advance development of mRNA therapeutics.
  • Drive innovative science to deliver novel mRNA designs.
  • Develop, evaluate, and implement new molecular biology technology and optimize existing techniques and workflows, while maintaining competitive scientific awareness, engage in scientific network.
  • Perform wide range of cell biology and optical microscopy assays, including functional assays, flow cytometry, and multiplex detection of mRNA and/or protein.
  • Maintain and enhance current knowledge of emerging technologies in bio-analytics and biophysical characterization to support continuous improvement of analytical strategies.

 

  • Author and review SOPs, reports and other technical documents and regulatory submissions.

 

  • Analyze data with available bioinformatic tools, scientifically-sound interpretation and present the data to internal and external stakeholders.

Qualifications

  • PhD in molecular biology, molecular virology or cell biology, or similar with at least 3+ years’ hands-on research experience, or MS in similar fields with at least 10 years of research experience.
  • Very strong molecular biology, RNA, and oligonucleotide background with extensive hands-on experience in cell-based applications.
  • Experience with CRISPR assays, specifically in cell lines
  • Experience in cell culture with model cell lines, e.g. HeLa, HEK293
  • Hands on experience and expertise in molecular cloning, in vitro transcription, analytical tools of DNA, RNA and protein (gel electrophoresis, enzyme reactions, immunoblotting, ELISA, Nanodrop, fragment analyzer), qPCR and/or ddPCR.
  • Understanding of cell biology, cell culture tools, fluorescence and confocal microscopy, quantitative image analysis, flow cytometry.
  • Experience establishing functional cell-based assays.
  • Demonstrated ability/willingness to quickly learn and perform in new areas, implement new techniques and instrumentation.