Principal Scientist, Assay Development

HireMinds has partnered with a pioneer in advanced cell culture systems for drug discovery.  They are revolutionizing preclinical drug discovery with their cutting edge technology and microphysiological systems (MPS).

We are looking for a Principal Scientist who will collaborate with a team of bioengineers, material scientists, and biologists to deliver on milestones set up for our programs, ensuring to meet timelines and present desirable results. The successful candidate will be self-motivated and have demonstrated exceptional communication, organizational, and leadership skills to work in a fast-paced environment.


  • Design, plan, and manage cell-based assays and experiments according to program objectives

  • Define and adapt program goals based on experiment results

  • Evaluate, analyze and report experiment results

  • Manage team of scientists to deliver on program objectives

  • Stay abreast of the latest scientific understanding in project specific biology from target validation to clinical data


  • Advanced degree (MS or PhD) 

  • Significant industry experience in drug discovery hit-to-lead process
  • Experience managing others and leading small teams
  • Expertise in primary and stem cell culture

  • Experience with design, execution, and analysis of diverse cell biology and tissue engineering experiments

  • Experience with advanced microphysiological models or 3D culture systems

  • Proficiency in a broad range of cell-based assays and assay development

  • Proficiency in general molecular biology techniques

  • Proficiency with characterization and analytical techniques

  • Hands-on experience with fluorescence and confocal microscopy

  • Mechanical analysis and characterization

  • Extensive experience documenting, analyzing, interpreting experimental data

  • Strong written and verbal communication skills