Director, Peptide Formulation & Technology (Early Phase)
Location: California (East Bay)
On-site commitment: 4 days a week
Job Description:
HireMinds is partnered with a biotech company focused on peptide drug development, with a vision of bringing commercial products to market. We are seeking a Pre-formulation expert with a discovery mindset to drive technical innovation and provide leadership in peptide delivery and pharmaceutical development. In this role, you will lead innovations in peptide delivery, including solid oral, liquid, and other novel delivery methods, from preclinical dosing studies through to clinical-phase scale-up. You will be a hands-on leader who enjoys working on-site and occasionally in the lab to integrate new formulation technologies and impart knowledge to the scientific team. If you are passionate about helping a team of experts develop clinically relevant peptide therapies for patients in need, we encourage you to apply today!
Your Responsibilities:
- Provide strategic guidance in identifying and implementing enabling technologies for peptide delivery systems and novel formulations.
- Lead peptide formulation development from lead optimization through clinical development, with expertise in formulation, pre-formulation research, process selection, and enabling technologies.
- Oversee technical aspects of formulation development, including work outsourced to CDMOs and contract testing laboratories.
- Manage pre-formulation and research formulation activities and oversee direct reports in laboratory duties.
- Collaborate with cross-functional teams across discovery, preclinical, and manufacturing stages to provide expertise in drug delivery formulations that enhance peptide oral bioavailability.
- Guide formulation and process development for biologics and/or peptides for oral and injectable routes, including controlled-release formulations.
- Apply principles of chemistry or pharmaceutical sciences to peptide formulation development.
- Effectively communicate study results and experimental data to project teams and senior management.
- Collaborate with external quality control, quality assurance, and regulatory personnel to ensure proper protocols and quality data capture.
- Implement and oversee cGMP principles and CDMO management for GMP manufacturing.
- Contribute to regulatory submissions by authoring relevant sections on formulation.
You’ll Bring:
- PhD in a formulation-related discipline, with 10+ years of experience in formulation and pre-formulation development in prior biotech or pharmaceutical settings.
- Expertise in drug delivery formulations to enhance peptide oral bioavailability.
- Strong analytical skills related to formulation.
- Current knowledge of peptide delivery systems (oral, liquid, and subcutaneous).
- Excellent communication skills for conveying technical results and project outcomes, with strong interpersonal skills for engaging diverse audiences.
- Experience collaborating with CMC team members and R&D project teams.
- Ability to travel to CDMO partners domestically and internationally.
Compensation:
Salary: $195,000 to $235,000
Bonus: 15-20%
Stock considerations, health, dental, and 401k plan