Director, Biochemistry and Assay Development

Director, Biochemistry and Assay Development
Hybrid / Full-time
Must be located in NYC Metro Area or MA

Our client, a NYC & Boston-based pre-clinical stage biotech pioneering small molecule medicines for targeted protein stabilization, is seeking a Director of Biochemistry and Assay Development to join their team.

Interested? If you meet the requirements below, please email me!

You will:

  • Lead junior staff, assay development and validation efforts internally
  • Oversee external CRO automation and data generation efforts / Review and confirm data from CROs
  • Generate, develop, and execute quantitative cell-based assays to triage compounds using a variety of readout technologies (fluorescence, luminescence, BRET)
  • Perform standard cell-based analytical analyses to assess protein levels, including flow cytometry, ELISA, immunoblotting/fluorescence, and cell imaging
  • Stay abreast of the latest scientific understanding in project specific biology from target validation to clinical data


  • Ph.D. in in Biology, Biochemistry, Chemical Biology or similar
  • Experience managing CROs
  • Proficiency in aseptic mammalian cell/tissue culture is a must
  • Expertise in biochemical assay development and validation
  • Expert in molecular biology techniques, with experience in CRISPR-based engineering of KO/KI cell lines desired 
  • Experience in Oncology/IO, Immunology, or Rare Diseases