Associate Scientist, AAV Downstream Process Development

Associate Scientist, AAV Downstream Process Development
South San Francisco, California

Who Are We?

Our client’s work is based on the science of their founder – one of the original CRISPR co-inventors who then furthered the technology so that DNA does not need to be cut to accomplish gene regulation.

Their Process Development team is looking to bring on board a Sr. Research Associate/Associate Scientist.  This individual will be a key member of the Process Development team, performing primarily downstream process optimization activities for AAV based production platform. 


  • Support development of a suspension cell AAV production platform in-house.
  • Conduct studies to enable development of representative scale down models for manufacturing processes.
  • Design and conduct experiments to assess critical and key process parameters and process controls and study their impact on critical quality attributes for AAV production.
  • Analyzing and interpreting experimental results; suggesting changes or additional experiments to improve the robustness and/or reproducibility of the production process.
  • Conduct dPCR and flow cytometry experiments and analysis.
  • Thorough documentation of experimental data and analysis
  • Sample inventory maintenance. 


  • BS degree in Cell Biology, Biochemistry, Biology or a related discipline plus a minimum of 3-4 years of experience as a research associate within a biotech or pharmaceutical company. 
  • Experience using DOE software to design experiments a key plus
  • Meticulous attention to detail and demonstrated experience of carefully recording methods and results.
  • Proven and consistent work ethic.  Self-directed; open to challenges with enthusiasm.
  • A strong aptitude to learn and take on new challenges.
  • Outstanding collaboration, problem solving team player with excellent communication and organizational skills.
  • Experience in mammalian cell culture (both adherent and suspension), aseptic techniques, transfections and analytical techniques such as PCR and flow cytometry
  • Prior experience working in a fast-paced, start-up environment.