Associate Director, Bioanalytical Bioassays (RNA/DNA/Oligos)

Associate Director, Bioanalytical Bioassays (RNA/DNA/Olgios)

 HireMinds is working with a top local gene therapy partner to find an experienced Bioanalytical bioassay developer.  In this role you will provide expertise with managing a team focused on analytical methods for nucleic acid (RNA/DNA/Oligos) gene delivery vectors both viral and non-viral forms. You will ideally be able to help devise and execute a variety of gene therapy analytical methods and related bioassays in testing and characterization of materials. As the leader of a group of assay designers you also will contribute across internal and external gene therapy collaborations as a resident expert along R&D and CMC stages of product lifecycle. If you have interest in hearing more contact the HireMinds biotech team today to learn more. 

As The Ideal Candidate You Duties Will Include: 

  • You will lead a team of analytical scientists and bioassay developers in design and execution of  analytical assays and experiments. 
  • You will also represent the Analytical & Bioassay team and provide expertise in analytical methods and bioassay program contributions 
  • Encourage cross-talk between the Analytical team in collaboration within the greater organization for a variety of programs
  • Maintain oversight of project progression and experiment prioritization and then analyze and communicate effectively to key stake holders and project members within the organization
  • Provide subject matter expertise and leadership in developing analytical methods for nucleic acid gene delivery vector candidates characterization for research grade vectors used in preclinical research.
  • Lead and oversee the Analytical & Bioassay team in duties related to transfer of methods to CMC teams which are involved in vector characterization
  • Coordination of international shipments of viral vectors and reagents among internal sites and external CRO and CMO partners
  • You will provide expertise to project teams as program progress from discovery to preclinical and into pharmaceutical development stages as a gene therapy vector analytical expert in turn guiding pipeline progression
  • Responsibility for budgets and shipping demands for bioassay and vector deliverables
  • You will have the ability to manage many competing demands across a variety of projects and maintain group has resources to meet demands

Candidate Requirements: 

  • Ph.D. degree in Bioanalytical, Immunology, or Biochemistry disciplines with 10+ years of  industry experience
  • Expertise in characterization RNA, DNA, and Oligonucleotide therapies with viral or non-viral delivery
  • Past proficiency and hands-on lab skills in cell-based assays, protein quantitation with ELISA, qPCR methods, and other plate-based assays are required
  • Experience with gene therapies and vector design using viral approaches is required
  • Expertise with establishing analytical methods and conducting analytical and bioassays in viral vector characterization.
  • Past exposure to supporting CMC teams for research grade GLP viral and non-viral product characterization
  • Ability to design protocols, data capture, and analysis for regulatory contributions for filings
  • Strong communication abilities and hunger to keep up-to-date on latest bioanalytical gene therapy technologies and techniques in the field